Expression of neighbor of Punc E11 in hepatocarcinogenesis induced by diethylnitrosamine
نویسندگان
چکیده
منابع مشابه
Role of CYP2E1 in diethylnitrosamine-induced hepatocarcinogenesis in vivo.
CYP2E1 metabolizes many low-molecular weight toxins and carcinogens. Some in vitro experiments suggest that CYP2E1 may be involved in the metabolic activation of diethylnitrosamine. However, there has been no direct evidence demonstrating a role for CYP2E1 in diethylnitrosamine-mediated carcinogenesis in vivo. To clarify this, we carried out a diethylnitrosamine-induced hepatocarcinogenesis exp...
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15 صفحه اولMetformin inhibits early stage diethylnitrosamine‑induced hepatocarcinogenesis in rats.
Antitumor effects of metformin have recently emerged despite its original use for type II diabetes. In the present study, the effects of metformin on the development and recurrence of hepatocellular carcinoma (HCC) were investigated using the diethylnitrosamine (DEN)‑induced rat model of HCC. Tumor foci were characterized by gross examination and by histopathological characteristics, including ...
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ژورنال
عنوان ژورنال: Oncology Reports
سال: 2014
ISSN: 1021-335X,1791-2431
DOI: 10.3892/or.2014.3285